NADH:ubiquinone oxidoreductase subunit B5 pseudogene 2 (NDUFB5P2)

NDUFB5P2 is a pseudogene, meaning it is a DNA sequence related to the functional gene NDUFB5, but it does not encode a functional protein product in humans. While NDUFB5 encodes a subunit of mitochondrial respiratory chain complex I with roles in electron transport and energy metabolism, NDUFB5P2 lacks protein-coding potential and is not involved in catalytic, regulatory, or structural functions associated with the active complex. There is no evidence suggesting NDUFB5P2 plays a role in disease, serves as a drug target, interacts with drugs, or is used for biomarker purposes. The inclusion of “pseudogene” in the name and its locus type (pseudogene) indicate this gene is non-functional and not actively involved in biological or disease processes. There is nothing to suggest it is misspelled, but reporting it as a target would be incorrect because pseudogenes are not conventional drug targets, receptors, or enzymes. NDUFB5P2 should be excluded as a drug target or functional receptor/enzyme/transporter in structured databases. It is a classic example of a gene misidentification scenario: the functional gene is NDUFB5, but NDUFB5P2 is merely a related non-coding pseudogene.

Other names

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa pseudogeneNDUFB5P2NADH:ubiquinone oxidoreductase subunit B5 pseudogene 2