NADH:ubiquinone oxidoreductase subunit B9 pseudogene 1 (NDUFB9P1)

NADH:ubiquinone oxidoreductase subunit B9 pseudogene 1 (NDUFB9P1) is classified as a pseudogene, meaning it is a non-functional genomic DNA sequence similar to a functional gene but does not encode a functional protein product. It is related to the functional gene NDUFB9, which encodes an accessory subunit of mitochondrial complex I (NADH dehydrogenase), but NDUFB9P1 itself is not transcribed or translated into an active enzyme and does not act as a therapeutic target or participate in biological pathways[1][7]. **Explanation and Supporting Details:** - **Pseudogene Status:** NDUFB9P1 is explicitly referred to as a **pseudogene** in all genome resources, indicating that it does not produce a functional protein and is not itself active in biochemical processes[1][7]. - **No Functional Activity:** There are no described biological functions, roles in disease, drug interactions, or biomarker uses associated with this gene, as is typical for pseudogenes. The related functional gene is NDUFB9[5][6], but NDUFB9P1 does not share these properties. - **Is Incorrect as a Drug Target:** Because NDUFB9P1 is a pseudogene and not a protein-coding gene, **it is not considered a therapeutic target**, nor is it a receptor, enzyme, transporter, or other target class relevant for drug development[1][7]. - **Molecular Classification:** The only accurate molecular category is "Other (Pseudogene)" rather than any functional molecular family (e.g., enzyme or receptor). - **Aliases:** The aliases provided are alternative, descriptive names referencing its relationship to the functional gene and protein[1]. - **No Disease Roles:** While dysregulation of functional mitochondrial complex I subunits (such as NDUFB9) is associated with mitochondrial disease, there is no evidence that the pseudogene NDUFB9P1 is involved in such conditions[1][5][6]. If you require structured information for the functional protein, search for "NADH:ubiquinone oxidoreductase subunit B9 (NDUFB9)." The entry above specifically describes the **pseudogene NDUFB9P1**, which is non-functional.

Other names

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa pseudogeneNADH:ubiquinone oxidoreductase subunit B9 pseudogeneNDUFB9P1