Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Neisseria meningitidis Capsular Polysaccharide (Serogroup Y) (CPS (Serogroup Y))
- Target
- CPS (Serogroup Y)
- Molecular classification
- Polysaccharide, Capsular Polysaccharide
01
Overview
The capsular polysaccharide of Neisseria meningitidis serogroup Y is a crucial virulence factor that protects the bacterium from host immune defenses. It is composed of repeating units containing sialic acid linked to glucose or galactose. The capsule's antiphagocytic properties enable survival in the bloodstream, leading to septicemia and meningitis. As a key antigenic determinant, it serves as the basis for serotyping, diagnostic assays, and vaccine design. Vaccines targeting Serogroup Y CPS aim to induce protective antibodies, preventing invasive disease.
- Other names
- Serogroup Y CapsuleGroup Y Meningococcal PolysaccharideN. meningitidis Serogroup Y CPS
02
Mechanism of action
Antibody-mediated opsonization and complement activation (for antibodies); Induction of antibody production (for vaccines)
03
Biological functions
Immune evasionAntiphagocytosisComplement inhibitionVirulence factor
04
Disease associations
MeningitisSepticemiaInvasive Meningococcal Disease
05
Safety considerations
Capsular switching leading to vaccine evasionPotential for autoimmune responses (rare)Vaccine side effects (minor, e.g., fever, injection site reactions)
06
Interacting drugs
Serogroup Y-specific antibodies
2 more in the full profile.
07
Biomarkers
Serogroup Y CPS detection in cerebrospinal fluid or bloodAnti-Serogroup Y CPS antibody titers
Beyond the preview
Go deeper on Neisseria meningitidis Capsular Polysaccharide (Serogroup Y) (CPS (Serogroup Y)).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Neisseria meningitidis Capsular Polysaccharide (Serogroup Y) (CPS (Serogroup Y)).