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The nervous system of *Pediculus humanus capitis*, the head louse, is essential for its survival, mediating sensory input, host detection, feeding, and environmental responses. It is the primary target for many pediculicidal treatments. The antennae are the primary sensory organs, containing various sensilla for detecting mechanical, thermal, hygroscopic, and chemical stimuli. Common pediculicides target components of the nervous system such as sodium channels, cholinesterase, and GABA receptors.
Various pediculicides target different components of the nervous system to disrupt nerve impulse transmission, leading to paralysis and death.
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