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Novel antisense transcript to EPH receptor A7 (EPHA7)

Molecular classification: Long non-coding RNA (lncRNA), Non-coding RNA

Overview

"Novel antisense transcript to EPH receptor A7 (EPHA7)" (ENSG00000287683) is a predicted long non-coding RNA gene transcribed from the DNA strand opposite to the protein-coding EPHA7 gene. While antisense lncRNAs frequently regulate their sense partner gene through transcriptional interference, RNA stability modulation, or chromatin remodeling, there is currently no experimental evidence clarifying the specific function of this antisense transcript. EPHA7 itself is a receptor tyrosine kinase involved in neural development and cancer, but the role of its antisense RNA, if any, remains unknown. As such, this transcript is neither a validated therapeutic target nor a known biomarker, and no drugs are known to interact with it[3][4].

Other names: Antisense RNA to EPHA7ENSG00000287683

Biological functions

Transcriptional regulation of EPHA7 (putative)mRNA stability or processing of EPHA7 (putative)

Disease associations

Other (Potential regulatory roles affecting EPHA7 are plausible, and EPHA7 is involved in cancer and neural development, but there is no documented direct implication for this antisense transcript in disease.)

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