Novel protein, readthrough between VTN and SEBOX (ENSG00000273171; also UniProtKB: H0YJW9)

This gene represents a computationally annotated readthrough transcript merging the VTN (vitronectin) and SEBOX (SEBOX homeobox) loci on chromosome 17. Such readthrough or "chimeric" transcripts can arise during transcription when the RNA polymerase ignores canonical termination signals and continues into adjacent gene loci, producing a hybrid mRNA molecule. The corresponding predicted protein is unvalidated, has no characterized function, no membership in any established protein family, and is not recognized as a molecular target for pharmacological agents. Current data categorizations (GeneCards, Ensembl, Protein Atlas) emphasize the absence of functional, tissue-specific, or disease-relevant information, and there is no evidence for its existence as a stable, functional protein product. Its annotation likely reflects automated genome annotation pipelines, and use as a molecular target or biomarker is not supported by the scientific literature. If you need a validated target related to VTN or SEBOX, queries should focus on vitronectin or SEBOX homeobox individually, which are established proteins with biological functions and target associations.

Other names

AC002094.3H0YJW9GC17M027144GC17M028366