Novel pseudogene, similar to phosphodiesterase 4D interacting protein PDE4DIP (AC239800.1)

ENSG00000223779 is a pseudogene in the human genome, annotated as “novel pseudogene, similar to phosphodiesterase 4D interacting protein PDE4DIP.” Pseudogenes are genomic DNA sequences similar to known genes but are typically nonfunctional due to accumulated disabling mutations such as frameshifts or premature stop codons. They do not encode functional proteins and are not druggable or bona fide therapeutic targets. Unlike its parent gene, PDE4DIP, which is involved in cellular signaling and cardiac contractility, ENSG00000223779 is not known to play any physiological or pathological role nor interact with any therapeutics. Pseudogenes can sometimes complicate molecular genetic studies due to sequence similarity with active genes, but their biological significance is usually minimal. If you are seeking information on the functional PDE4DIP protein, note that ENSG00000223779 refers only to a nonfunctional pseudogene related to it, not the active protein product.

Other names

AC239800.1Novel pseudogene similar to PDE4DIP

None (as nonfunctional DNA, pseudogenes do not have drug-related mechanisms of action)