Novel transcript, antisense to ADGRA2 (ENSG00000294776)

ENSG00000294776 is classified as a long noncoding RNA (lncRNA) gene, annotated on the human genome as a novel transcript antisense to ADGRA2. It does not encode a protein and has no established function, role in disease, or characterization as a therapeutic target. Its name indicates its genomic position is opposite (antisense) to the ADGRA2 (adhesion G-protein coupled receptor A2) gene, but there is no evidence for its involvement in any regulatory, disease-relevant, or pharmacological processes at this time[7]. *Note:* The entry may appear in some datasets due to transcriptome mapping and gene annotation efforts, yet it is not considered a druggable target or a functionally characterized biomolecule. There is no indication of misspelling or misannotation, but the gene’s designation is descriptive rather than functional or canonical. For the actual protein-coding GPCR, see ADGRA2 (GPR124)[1][2][3][6][7], which is a known GPCR involved in brain angiogenesis and Wnt signaling.

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