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This entity represents a long non-coding RNA transcript (lncRNA) annotated antisense to the AP1S2 gene. Its sequence overlaps or is opposite to the AP1S2 coding region, but it is not known to encode a functional protein or have a characterized role in molecular biology or disease. Antisense lncRNAs can sometimes act as regulators of sense gene transcription or post-transcriptional events, but for ENSG00000307891, there is no experimental evidence or disease linkage described in current databases. The AP1S2 gene itself encodes the sigma 2 subunit of the clathrin-associated adaptor protein complex 1, which is involved in protein sorting in the Golgi- and trans-Golgi network and has disease relevance in certain inherited mental retardation syndromes. If searching for a classical drug target, this transcript is likely not relevant. The AP1S2 gene/protein would be the relevant entity for traditional target information.
None characterized.
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