Target intelligence / Profile preview

Novel transcript, antisense to CCDC149 and LGI2 (LOC102723675)

Target
LOC102723675
Molecular classification
Other (long non-coding RNA, antisense RNA)
01

Overview

LOC102723675 is an uncharacterized human non-coding RNA gene (long non-coding RNA, or lncRNA) that is transcribed antisense to the CCDC149 and LGI2 genes. It is annotated as a novel non-coding transcript without evidence of protein-coding potential. Long non-coding antisense RNAs are often involved in regulation of gene expression by diverse mechanisms, such as modulating transcription of overlapping or neighboring sense genes, influencing local chromatin structure, or affecting RNA stability and translation. No functional studies, disease associations, or drug interactions are presently reported for this specific transcript.

Other names
LOC102723675ENSG00000298600Novel transcript, antisense to CCDC149 and LGI2GC04U901822GC04P024993
02

Mechanism of action

Not applicable; no drugs or therapies are known to act on this transcript

03

Biological functions

Most antisense non-coding RNAs are implicated in gene regulation, including transcriptional and post-transcriptional regulation, epigenetic modifications (such as DNA methylation and histone modification), and possible roles in chromatin remodelingSpecific function for LOC102723675 remains uncharacterized
04

Disease associations

No direct association with disease has been described for this transcriptNatural antisense transcripts in general are sometimes implicated in cancer, epigenetic dysregulation, and imprinting disorders, but no evidence connects LOC102723675 specifically to such roles
05

Safety considerations

None
06

Interacting drugs

None known
07

Biomarkers

None known

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