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Novel transcript, antisense to CD44

Molecular classification
Other (long non-coding RNA; lncRNA)
01

Overview

ENSG00000309480, annotated as "Novel transcript, antisense to CD44," represents an uncharacterized long non-coding RNA (lncRNA) whose sequence is antisense or overlaps the region of the protein-coding gene **CD44**[4]. There is no standardized, canonical name or abbreviation for this transcript and no evidence it acts as a therapeutic target (such as receptor, enzyme, transporter, or similar entity). The transcript is not established in functional studies, has no documented aliases, drug interactions, mechanisms of action, or value as a biomarker. Its molecular classification is "Other" (lncRNA). The biological significance of this transcript remains unknown; while lncRNAs in antisense orientation to protein-coding genes can sometimes modulate gene expression, there is no direct evidence for such a regulatory role in this case. There is nothing indicating this is a conventional, actionable drug target. This entity is flagged as "incorrect" for therapeutic target queries, as it does not meet the definition of a druggable or disease-associated target, and most database resources classify it solely as an uncharacterized lncRNA overlapping CD44[4].

02

Mechanism of action

None known

03

Biological functions

Unknown (no direct biological function annotated; possible regulatory role on CD44 expression by antisense transcription, but this is speculative)
04

Disease associations

Other (no direct disease association formally established; CD44 itself is associated with several diseases, but this specific antisense transcript is uncharacterized)

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