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Novel transcript, antisense to CD6 (None established; sometimes shortened to "antisense to CD6" or referenced by its Ensembl ID "ENSG00000303405")
- Target
- None established; sometimes shortened to "antisense to CD6" or referenced by its Ensembl ID "ENSG00000303405"
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense transcript
01
Overview
Novel transcript, antisense to CD6 (ENSG00000303405), is a long non-coding RNA located antisense to the CD6 gene locus. It is classified as a lncRNA and might participate in the post-transcriptional regulation of CD6, either by influencing mRNA stability, alternative polyadenylation, or gene expression, as observed with other antisense RNA species[4][7]. There is evidence that antisense transcripts are subject to RNA editing, which can result in immunogenic double-stranded RNA structures[1]. However, there is currently no experimental data describing the specific biological role, mechanism, or disease relevance of ENSG00000303405, nor is it recognized as a therapeutic target, biomarker, or drug-interacting molecule. The information available is primarily limited to sequence-based annotation and transcriptomic classification within the human genome[4].
- Other names
- Novel transcript, antisense to CD6ENSG00000303405GC11M137895
02
Mechanism of action
None applicable. No drugs are reported to target this lncRNA.
03
Biological functions
Putatively involved in regulation of CD6 gene expression (typical for antisense RNAs, based on general lncRNA and antisense RNA biology, not demonstrated specifically for this transcript)May participate in RNA editing or be subject to A-to-I editing, which can influence immunogenicityOther: Currently no direct experimental evidence for additional functions
04
Disease associations
Other: No direct associations with disease described for this specific transcript. CD6 itself has links to autoimmunity such as multiple sclerosis, but the disease relevance of this antisense transcript is not documented
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