Target intelligence / Profile preview

Novel transcript, antisense to CD97 (None)

Target
None
Molecular classification
Long noncoding RNA (lncRNA), Natural antisense transcript (NAT)
01

Overview

The "novel transcript, antisense to CD97" (ENSG00000267379) is a long noncoding RNA (lncRNA) gene identified in the human genome and is transcribed antisense to the CD97 coding gene. Antisense transcripts such as this can regulate expression of their corresponding sense gene (in this case, CD97) by mechanisms including chromatin modification, transcriptional interference, and modulation of transcript stability[2][5][10][11]. Although widespread and functionally important as a type of gene expression regulatory RNA, these transcripts are not typically considered classical therapeutic targets such as receptors or enzymes, and no drugs are reported to directly interact with this particular transcript. Antisense lncRNAs have emerged as significant in fine-tuning cellular processes, but specific molecular and disease roles for ENSG00000267379 remain largely uncharacterized, with suggestive links to immune cell contexts due to CD97 function[4][1].

Other names
ENSG00000267379Novel transcript, antisense to CD97
02

Mechanism of action

Not applicable. As a noncoding RNA, it is not directly targeted by drugs; experimental approaches have used antisense oligonucleotides to modulate the function of other NATs, but not specifically this one

03

Biological functions

Transcriptional regulation (through antisense mechanisms)Chromatin modification (influences sense transcription via epigenetic changes)Regulation of mRNA stability and processing in nearby/sense genes
04

Disease associations

Other (Possible roles in immune cell function, but specific roles remain unclear; may have general relevance to conditions where CD97 expression or immune system regulation is altered)
05

Safety considerations

None specifically reported. Modulating long noncoding RNAs and NATs may have off-target effects due to their role in global gene regulation, but this is a general concern for RNA-targeted therapeutics
06

Interacting drugs

None directly reported
07

Biomarkers

None specifically reported for this transcript

Beyond the preview

Go deeper on Novel transcript, antisense to CD97 (None).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Novel transcript, antisense to CD97 (None).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call