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novel transcript, antisense to Chromosome 19 open reading frame 66

Molecular classification
Non-coding RNA
01

Overview

The "novel transcript, antisense to Chromosome 19 open reading frame 66" (ENSG00000267387) is an uncharacterized non-coding RNA located on the antisense strand of the C19orf66 gene region. Unlike the well-studied sense strand product C19orf66 (also known as SHFL, RyDEN, IRAV), which encodes a protein with broad-spectrum antiviral activity, this antisense transcript has no direct evidence of protein-coding potential, biological activity, or disease association in currently available research. Its function may be related to cis-regulatory effects on C19orf66 expression, as is often seen with antisense RNAs, but such a role has not been experimentally validated for this specific transcript. This entry is not considered a canonical therapeutic target, and its biological significance remains unknown[4][9].

Other names
antisense transcript to C19orf66antisense RNA (to SHFL, RyDEN, IRAV, C19orf66)
02

Biological functions

Potential regulation of C19orf66 expression via antisense interaction (speculative, common for antisense transcripts)Other (no specific biological activity established in literature)
03

Disease associations

Other (no established disease association)

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