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Novel transcript, antisense to ERVK3-1 (ENSG00000283103)
- Target
- ENSG00000283103
- Molecular classification
- Antisense RNA, Non-coding RNA
01
Overview
This locus produces a long non-coding RNA that is transcribed antisense to the ERVK3-1 gene region. ERVK3-1 encodes a retrovirus-derived protein and is part of the human endogenous retrovirus K (HML-6) family. ERVK3-1 itself is expressed in multiple tissues and has shown increased activity in some cancers, such as melanoma and breast cancer; however, the specific role or function of the antisense transcript (ENSG00000283103/LOC105372480) is not documented and remains unknown. It is not categorized as a receptor, enzyme, transporter, or other canonical therapeutic target and is currently considered a non-coding regulatory element with uncharacterized biological roles[1][3].
- Other names
- LOC105372480novel transcript, antisense to ERVK3-1
02
Biological functions
Potential regulation of ERVK3-1 expressionUnclear/no confirmed function
03
Disease associations
Possible but uncharacterized links via ERVK3-1/ERVK/HML-6 retroviral activations in cancer
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