Target intelligence / Profile preview

Novel transcript, antisense to ESPN (ENSG00000231868)

Target
ENSG00000231868
Molecular classification
Long non-coding RNA (lncRNA)
01

Overview

ENSG00000231868, also known as "novel transcript, antisense to ESPN," is a long non-coding RNA annotated on the human genome as transcribed antisense to the ESPN gene. Biological functions of antisense lncRNAs can include modulation of sense gene expression via chromatin modification, transcriptional interference, RNA masking, or generation of double-stranded RNA structures, but there is no specific functional data for this lncRNA. It is not considered a therapeutic target, nor is it implicated directly in disease or known to interact with drugs.

02

Biological functions

Modulation of gene expression through antisense transcriptionPossible regulation of ESPN gene expression via mechanisms common to antisense RNAs such as transcriptional interference, RNA masking, and chromatin remodeling
03

Disease associations

No direct disease associations have been described for this transcript.The ESPN gene (the sense gene) is associated with neurosensory deafness, but there is no evidence this antisense transcript itself impacts disease.

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