Novel transcript, antisense to filamin B

ENSG00000303089, described in Ensembl as a \"novel transcript, antisense to FLNB,\" refers to a predicted or low-confidence RNA molecule transcribed from the opposite strand of the FLNB gene (filamin B), a gene encoding a cytoskeletal protein. There is no evidence that this antisense transcript is a validated, functional molecule or that it serves as a therapeutic target, biomarker, or drug-interacting locus. Antisense transcripts in general are a class of non-coding RNAs that can modulate gene expression through diverse mechanisms, such as transcriptional interference, chromatin remodeling, or RNA duplex formation[3][5][1][4]. However, for ENSG00000303089, there is a lack of experimental characterization or disease relevance. This entry is likely a product of high-throughput genome annotation and should not be considered a canonical biological target without further evidence.

Other names

novel antisense transcript to FLNBENSG00000303089may be listed as "antisense to FLNB" in some annotations