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This is a long non-coding RNA transcript, specifically antisense to the HPGDS (hematopoietic prostaglandin D synthase) gene. Antisense transcripts, including those located opposite coding genes, can regulate gene expression by influencing chromatin state, modifying transcription dynamics, or affecting mRNA stability of their sense counterparts[3][5]. While antisense transcripts are widespread and biologically significant for the regulation of gene expression, most do not encode proteins and are not classical therapeutic targets such as receptors or enzymes. There is currently no evidence that this particular antisense transcript is used as a drug target or biomarker. The entry ENSG00000287552 is primarily notable as a genomic annotation rather than a molecular entity relevant for pharmacological targeting[1][5].
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