novel transcript, antisense to KIAA0825 (ENSG00000286577)

This entry corresponds to a non-coding antisense RNA transcript located antisense to the KIAA0825 gene region. There is no evidence that it encodes a protein. Antisense transcripts can sometimes regulate the expression of their sense counterparts (in this case, the protein-coding KIAA0825), but no specific functional, therapeutic, or disease-modulating activity is established for this transcript. Its biological significance, if any, would be through potential RNA-RNA or RNA-protein interactions, but these have not been characterized. The nomenclature LOC105379087 is an automated designation and does not correspond to a known, well-characterized gene product. KIAA0825, the sense gene, is a protein-coding gene linked to limb development and possibly diabetes and polydactyly phenotypes. However, antisense transcripts such as ENSG00000286577 are catalogued as non-coding and not recognized as direct therapeutic or diagnostic targets. Multiple public databases (e.g., Open Targets, E2G, Ensembl) classify ENSG00000286577 as an "intron variant, non coding transcript variant" in relation to KIAA0825.

Other names

LOC105379087ENSG00000286577Novel transcript, antisense to KIAA0825