Novel transcript, antisense to leukotriene A4 hydrolase

ENSG00000307169 ("novel transcript, antisense to LTA4H," "LOC124902990") is a long non-coding RNA gene located antisense to the protein-coding gene LTA4H (leukotriene A4 hydrolase)[5]. Unlike LTA4H, which encodes a zinc-dependent enzyme involved in leukotriene B4 biosynthesis and inflammatory pathways[1][7], this transcript does not code for a protein and has no known direct function or role in disease. Its presence may indicate a potential regulatory relationship with LTA4H, but as of current knowledge, it is not characterized as a functional or therapeutic molecular target, nor is it implicated in pharmacology or used as a biomarker. If structured information about LTA4H itself (the protein) is needed, this is a distinct, well-characterized enzyme involved in pro-inflammatory mediator synthesis[1][3][7]; however, ENSG00000307169 refers to an uncharacterized antisense lncRNA gene adjacent to LTA4H and not the enzyme itself[5].

Other names

ENSG00000307169LOC124902990novel transcript antisense to LTA4H