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Novel transcript, antisense to NOTCH2NLB and NBPF14 (LOC105371223)
- Target
- LOC105371223
- Molecular classification
- Noncoding RNA, Antisense RNA
01
Overview
LOC105371223 (ENSG00000301230) is an uncharacterized noncoding RNA gene annotated as a novel antisense transcript located opposite to the protein-coding genes NOTCH2NLB and NBPF14. It is classified as an antisense RNA, which in general can impact transcription or chromatin state of nearby genes by mechanisms such as altering nucleosome positioning, histone modification, and transcript processing rates. However, the specific function, biological relevance, and therapeutic implications of LOC105371223 have not been elucidated. There is currently no evidence supporting its status as a drug target, its clinical relevance, involvement in disease, or use as a therapeutic biomarker. The locus itself is uncharacterized and may represent a transcript with only putative regulatory or epigenetic effects, with no direct functional evidence.
- Other names
- Novel transcript antisense to NOTCH2NLB and NBPF14LOC105371223ENSG00000301230
02
Biological functions
Possible regulation of the expression of NOTCH2NLB and NBPF14 through antisense transcription, influencing chromatin and transcriptional dynamicsSpecific biological role is unconfirmed
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