Novel transcript, antisense to NPIPA3

ENSG00000305462 refers to a non-coding RNA gene named *novel transcript, antisense to NPIPA3*. It is located antisense to the NPIPA3 locus, which encodes Nuclear Pore Complex Interacting Protein Family Member A3. No protein product is described for this transcript, and no functional characterization, disease relevance, or therapeutic targeting is reported in current genomic databases. Its inclusion in target lists may be due to incomplete annotation or misclassification, as it lacks properties of canonical drug targets such as receptors, enzymes, or transporters. GeneCards and other gene databases recognize ENSG00000305462 as an "RNA Gene" without protein-coding capacity or established function. Antisense transcripts are often annotated in reference genomes, but many lack functional validation or therapeutic significance unless experimentally demonstrated. The relationship to NPIPA3 (a genuine protein-coding gene) is purely positional and does not impart target status. There is no evidence for involvement in signaling, regulation, disease mechanisms, or drug interaction. The protein-coding gene in the region, NPIPA3 (Nuclear pore complex interacting protein family member A3), is distinct and not described as a major therapeutic target. This transcript should not be considered a druggable entity or a classic biological target category. Its listing may stem from genome annotation artifacts or incomplete data, and it does not meet the criteria for structured target curation.

Other names

ENSG00000305462novel transcript antisense to NPIPA3antisense NPIPA3 RNA