Novel transcript, antisense to PDCD2

This entry refers to a novel long noncoding RNA transcript that is antisense to the PDCD2 (Programmed cell death protein 2) gene, annotated as ENSG00000267024 in Ensembl and LOC124904695 in some NCBI/RefSeq records. It is mapped as an antisense RNA overlapping the PDCD2 gene locus, potentially regulating PDCD2 expression via transcriptional interference, a phenomenon described for similar conserved antisense transcripts in mouse, chicken, and human[2]. However, there is no published experimental evidence attributing a confirmed biological function, disease association, or relevance as a therapeutic target, biomarker, or drug-interacting molecule[5][2]. Entries like this in genomic datasets often remain poorly characterized ("novel transcript" status), with some considered possible artifacts or incomplete annotation, as suggested by transcriptome studies[2]. Its principal relevance is as a genomic feature that may participate in regulatory mechanisms, not as a target for drug discovery or clinical intervention.

Other names

ENSG00000267024LOC124904695AC008747.1Novel transcript, antisense to PDCD2

None established; antisense transcripts may interfere with sense transcription through transcriptional interference or RNA-based mechanisms, but specific drugs/mechanisms do not exist for this target