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novel transcript, antisense to PPP2R2C" is an annotated genomic transcript that is transcribed antisense to the **PPP2R2C** gene region. It does not encode a known protein, enzyme, receptor, transporter, or other characterized therapeutic target. Its biological function, disease relevance, and pharmacology are currently unknown or uncharacterized in the scientific literature. **Explanation and Key Context:** - **Antisense Transcripts**: These are RNA molecules transcribed from the opposite (antisense) DNA strand of a known gene—in this case, PPP2R2C, which codes for a regulatory subunit of protein phosphatase 2A (PP2A)[1][2][3]. Antisense RNAs can sometimes have regulatory roles but are not generally targets for conventional drugs, and are not classified among enzymes, receptors, transporters, etc. - **Database Entry**: ENSG00000295681 is an Ensembl gene ID that marks a non-coding transcript. There are no published functions, associations to molecular families such as GPCRs or kinases, disease relevance, or drug interactions available for "novel transcript, antisense to PPP2R2C". - **Therapeutic Target Status**: There is no evidence this molecule is a therapeutic target or biomarker, nor is its pharmacology described. The primary, well-studied product in this locus is **PPP2R2C**, which participates as a regulatory (B-gamma) subunit in PP2A and has some disease associations[1][2]; however, "novel transcript, antisense to PPP2R2C" is not the same as PPP2R2C and does not encode this protein. - **Potential Issues**: If you seek information about a disease/gene target, **PPP2R2C** is the canonical protein-coding gene of interest, not this antisense transcript.
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