Novel transcript, antisense to SHANK2 (ENSG00000286708)

This entry refers to a putative, uncharacterized noncoding RNA (natural antisense transcript) arising from the SHANK2 locus. Natural antisense transcripts (NATs) are a class of RNAs transcribed from the opposite strand of a protein-coding or noncoding gene; they often regulate their sense counterpart’s expression through transcriptional interference, RNA masking, chromatin remodeling, or double-stranded RNA mechanisms. The specific transcript “novel transcript, antisense to SHANK2” does not have any established function or role as a molecular target and is not classified as a receptor, enzyme, or other commonly targeted protein. Its presence in the genome annotation indicates it may play a regulatory role in modulating SHANK2 gene expression, which itself is involved in synaptic function and is implicated in neurodevelopmental disorders such as autism spectrum disorder; however, no direct functional or disease role for this antisense transcript has been established.

Other names

novel transcript, antisense to SHANK2

Not applicable (no drugs known to target this transcript)