Novel transcript, antisense to USP51

This gene encodes a long non-coding RNA (lncRNA) that is transcribed in the antisense orientation to the USP51 gene. Antisense lncRNAs frequently play regulatory roles in controlling expression of their associated sense genes, often through mechanisms involving chromatin modulation, transcription interference, or direct RNA interactions. While this specific transcript (ENSG00000288739) does not have a well-characterized function, antisense transcription in general can locally modify chromatin architecture, regulate transcription rates, and potentially affect gene expression of USP51. No clinical or drug interaction data are available for this target, and it is not currently classified as a therapeutic target.

Other names

lnc-USP51-2ENSG00000288739Novel antisense transcript to USP51

Chromatin modification (by analogy with the broader class of antisense RNAs; lncRNAs can recruit chromatin modifiers or impact chromatin status near their sense gene targets) Regulation of sense (USP51) gene expression (general role inferred for antisense lncRNAs)