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ENSG00000268678 is a poorly characterized, long non-coding RNA (lncRNA) transcript that is antisense to the known gene ZNF304. As a member of natural antisense transcripts (NATs), it is transcribed from the opposite DNA strand relative to the sense gene (ZNF304). Antisense transcripts can regulate gene expression through mechanisms such as transcriptional interference, altering chromatin structure, and affecting RNA processing or stability of the sense transcript. There is no direct evidence that this particular antisense transcript has a defined function or clinical relevance, nor has it been established as a therapeutic target. It is best categorized as a genomic feature of uncertain significance, typical for many lncRNAs annotated in the human genome.
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