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Novel transcript, antisense to ZNF429 (ENSG00000268081)
- Target
- ENSG00000268081
- Molecular classification
- Other, long non-coding RNA, antisense transcript
01
Overview
This gene locus produces a long non-coding RNA (lncRNA) that is transcribed antisense to the ZNF429 gene. It does not encode a protein. Antisense transcripts can modulate the expression of their sense gene counterparts through various mechanisms such as transcriptional interference, changes to chromatin state, or RNA duplex formation. There is currently no direct evidence for a specific biological function or disease association for this transcript. Antisense lncRNAs broadly are involved in gene regulation and may be relevant to disease, but this specific transcript is not recognized as a therapeutic target.
- Other names
- ENSG00000268081novel transcript, antisense to ZNF429
02
Mechanism of action
Not applicable for drugs, but antisense RNA mechanisms include: transcriptional interference, chromatin modification, RNA masking, dsRNA pairing, and RNA interference
03
Biological functions
Regulation of gene expression (by antisense transcription)chromatin modificationpotential impact on ZNF429 gene transcription
04
Disease associations
No specific disease association has been reported for this transcriptantisense lncRNAs as a class are implicated in processes such as cancer and neurodegeneration
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