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Novel transcript, antisense to ZNF696 (ENSG00000272172)

Target
ENSG00000272172
Molecular classification
Natural antisense transcript, Non-coding RNA
01

Overview

Novel transcript, antisense to ZNF696 (ENSG00000272172) is a non-protein-coding RNA transcribed from the strand opposite to the ZNF696 gene. Antisense transcripts such as this are broadly present in mammalian genomes, often overlapping the coding regions of sense genes. They are primarily thought to modulate the expression of their corresponding sense genes by altering chromatin structure, influencing transcript stability, or interfering with transcription and splicing[1][3][4]. While antisense transcription can contribute to gene regulation, particularly through epigenetic modification and RNA-based mechanisms, these molecules are not considered classic drug targets. Their potential functions in disease are linked primarily to their effects on the regulation of coding genes rather than direct pathological roles[1][3][4].

Other names
ENSG00000272172antisense to ZNF696
02

Mechanism of action

Regulatory effects via\n Modulating chromatin state (e.g. histone acetylation, methylation)\n Interfering with sense transcript production and stability\n Forming double stranded RNA duplexes (potentially leading to RNA interference pathways)

03

Biological functions

Chromatin modification and regulationRegulation of sense transcript expression and stabilityPotential involvement in RNA masking and transcriptional interference
04

Disease associations

May influence disease indirectly by regulating ZNF696 expression; specific disease links for this transcript are not reported

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