novel transcript, sense intronic to BFSP1 (ENSG00000277373)

ENSG00000277373 is a long non-coding RNA (lncRNA) gene located within an intron in the sense orientation relative to the protein-coding BFSP1 gene. It is a novel annotated transcript, has no known coding potential, no established biological function, and no evidence of involvement in disease or therapeutic mechanisms. Its clinical and biological significance is currently unknown. This transcript is not BFSP1 itself, but rather a non-coding gene found "sense intronic" to BFSP1, meaning it lies within a BFSP1 intron but on the sense strand. The closest protein-coding gene is DSTN, but BFSP1 is the main related gene mentioned in genomic databases. There is no evidence in the available data that this transcript encodes a receptor, enzyme, transporter, or similar pharmacologically actionable molecule. No disease or drug associations are present in reputable updates from Open Targets and other gene annotation platforms. BFSP1 (beaded filament structural protein 1, filensin) is a distinct, protein-coding gene involved in lens structure and associated with certain types of cataract, but ENSG00000277373 is separate from BFSP1. ENSG00000277373, "novel transcript, sense intronic to BFSP1," is a putative non-coding RNA locus within the BFSP1 gene’s intronic region. It lacks evidence of function, therapeutic relevance, and is not considered a canonical drug target.

Other names

ENSG00000277373novel transcript, sense intronic to BFSP1