Target intelligence / Profile preview

Novel transcript, sense intronic to UBE3A (ENSG00000261529)

Target
ENSG00000261529
Molecular classification
Other, Long non-coding RNA, lncRNA, RNA gene
01

Overview

ENSG00000261529 is a long non-coding RNA gene identified as a novel sense transcript within an intronic region of the UBE3A gene. Unlike UBE3A-ATS (the antisense transcript to UBE3A), which has a clear role in imprinting regulation and is implicated in neurodevelopmental disorders like Angelman and Prader-Willi syndromes[3][5], this sense intronic transcript lacks substantial published data regarding its molecular function, disease roles, or utility as a drug target or biomarker[1][3]. Most annotations describe it as an RNA gene of unknown function, not encoding a traditional protein or receptor[1]. It is not listed as interacting with drugs or as having any established mechanism of action in therapeutics.

Other names
Novel transcript, sense intronic to UBE3AENSG00000261529
02

Mechanism of action

None known. No mechanisms of drug action are established for this transcript.

03

Biological functions

Unknownmay be involved in regulation of UBE3A expression, but direct biological functions are not established
04

Disease associations

OtherPotential regulatory RNA in UBE3A locusno direct disease associations, unlike UBE3A-ATS which is involved in Prader-Willi/Angelman syndromes

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