Nuclear-encoded mitochondrial transfer RNA serine (anticodon UGA) 3-1 pseudogene (NMTRS-TGA3-1)

Nuclear-encoded mitochondrial transfer RNA serine (anticodon UGA) 3-1 pseudogene is a genomic DNA sequence in the human nuclear genome derived from a mitochondrial serine tRNA gene, likely inserted into the nucleus via DNA transfer from mitochondria over evolutionary time. Such pseudogenes are non-coding and do not produce functional RNA or protein. Although mitochondrial tRNAs are essential for mitochondrial translation and function in protein synthesis within mitochondria, nuclear-encoded tRNA pseudogenes have no direct role in mitochondrial biology, do not participate in tRNA processing or translation, and are not known to be relevant as therapeutic targets, biomarkers, or contributors to disease[2].\n\nIf you are interested in true mitochondrial serine tRNAs (for example, tRNA-Ser(AGY) or tRNA-Ser(UCN)), they are small non-coding RNAs encoded in the mitochondrial genome, essential for translation of mitochondrial-encoded genes, and their dysfunction can cause human disease[2][1].\n\nNote: The entity described here is not a protein or druggable target but a non-coding pseudogene. There is no evidence it is transcribed, translated, or implicated in disease, nor does it bind drugs or serve as a biomarker.

Other names

nmt-tRNA-Ser-TGA-3-1TRNAS30PNMTRS-TGA3-1nuclear-encoded mitochondrial transfer RNA-Ser (TGA) 3-1transfer RNA serine 30 (anticodon UGA) pseudogene

None. Not a drug target.