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P4HA2 antisense RNA 1 (non-protein coding) (P4HA2-AS1)
- Target
- P4HA2-AS1
- Molecular classification
- Other, Long non-coding RNA (lncRNA)
01
Overview
P4HA2 antisense RNA 1 (P4HA2-AS1) is a long non-coding RNA transcribed as the antisense complement of the protein-coding gene P4HA2. At present, there is virtually no empirical evidence supporting its function as a drug target, disease biomarker, or mediator of disease. Most references to P4HA2 in oncology, fibrosis, and other pathological states relate to the protein-coding enzyme prolyl 4-hydroxylase subunit alpha-2 (P4HA2), not this lncRNA. Therefore, this entry is not a canonical therapeutic target and should be distinguished from P4HA2. If your intent was to inquire about the protein-coding gene P4HA2 (prolyl 4-hydroxylase subunit alpha-2)—a validated target in oncology and tissue remodeling—please clarify, as its attributes differ significantly[1][2][3][5].
- Other names
- P4HA2 antisense RNA 1P4HA2-AS1P4HA2-AS1 (non-protein coding)
02
Biological functions
OtherNo well-established biological function specific to P4HA2-AS1, as opposed to the protein-coding P4HA2.
03
Disease associations
OtherNo direct evidence for its role in cancer, inflammation, or other diseases as an independent molecular entity at this time. The protein-coding P4HA2, not P4HA2-AS1, is implicated in cancer and tissue fibrosis[1][2][3][5].
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