Pathogenic bacteria (RUDN bacteriophage complex targets)

The target 'Pathogenic bacteria targeted by RUDN bacteriophage complex' refers to a specific group of bacterial pathogens, including Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli, which are susceptible to lytic phage cocktails studied at RUDN University (Peoples' Friendship University of Russia) (RUDN University, 2023). These bacteria are major drivers of pyoinflammatory diseases such as wound infections, respiratory tract infections, and sepsis (Microgen, 2022). The RUDN bacteriophage complex (often associated with the commercial 'Complex Bacteriophage' or 'Pyobacteriophage') targets these organisms by binding to specific surface receptors and initiating a lytic cycle that results in bacterial cell death (NIH, 2021). This approach is a critical area of research for addressing multi-drug resistant (MDR) infections where traditional antibiotics fail (PubMed, 2020). However, therapeutic challenges include the potential for bacteria to develop phage resistance and the risk of systemic inflammatory responses due to the release of endotoxins during rapid bacterial lysis (StatPearls, 2023).

Other names

Pyoinflammatory bacteriaBacteriophage complex targetsRUDN phage targetsComplex bacteriophage targets

Bacterial cell lysis via the lytic cycle of bacteriophages, involving adsorption to surface receptors, genome injection, and host cell hijacking.