Peanut Allergenic Proteins (Immune Response) (Peanut Allergy Response)

Immune system desensitization to peanut protein aims to reduce hypersensitivity in individuals with peanut allergy. It involves gradually increasing doses of peanut protein to raise the reaction threshold and mitigate risks from accidental exposure. Key allergens include Ara h 1, Ara h 2, and Ara h 6. Desensitization shifts the immune response towards tolerance, increasing protective antibodies and regulatory cells while decreasing allergy-driving factors. Treatment requires medical supervision due to the risk of allergic reactions.

Other names

Ara h 1Ara h 2Ara h 6Peanut proteinPeanut allergensDefatted peanut flour

Oral immunotherapy induces desensitization by modulating the immune response through repeated exposure to peanut protein, increasing IgG4, decreasing IgE, and expanding regulatory T cell populations.