PEST proteolytic signal containing nuclear protein, pseudogene (PCNP, pseudogene)

PEST proteolytic signal containing nuclear protein, pseudogene (ENSG00000270202) is annotated as a nonfunctional gene (pseudogene), meaning it does not produce a functional protein product. Its name is derived from its homology to PCNP, a nuclear protein containing PEST motifs (regions rich in Proline, Glutamic acid, Serine, Threonine) that function as proteolytic signals targeting proteins for degradation. Functional PCNP is involved in cell cycle regulation, apoptosis, protein ubiquitination, and tumorigenesis across several cancer types, and may be a research target for cancer therapy. However, this specific pseudogene lacks experimental evidence of biological function, disease involvement, or therapeutic targeting.

Other names

PEST-containing nuclear protein pseudogenePEST-containing nuclear protein