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In Traditional Chinese Medicine, \"phlegm transformation and opening sensory orifices\" refers to a group of therapeutic principles aimed at treating conditions believed to result from the accumulation of pathological \"phlegm\" (a conceptual pathological substance) and blockage of sensory orifices (such as unconsciousness, coma, or delirium)[1][2][3][5]. This is achieved through herbal prescriptions, acupuncture, and dietary or lifestyle modifications intended to restore normal fluid metabolism, clear \"phlegm,\" and thus improve consciousness and sensory function. There is no corresponding single molecular receptor or target in biomedical science to this TCM concept[2][3][5][7][8][9].
In TCM, herbs are believed to \"transform phlegm,\" \"resolve dampness,\" regulate Qi, and open blocked pathways to restore consciousness and clear sense organs; there are no directly corresponding mechanisms at the molecular or receptor level[7][8][9].
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