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The ENSG00000233995 locus corresponds to a pseudogene related to the phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA), a key enzyme in the PI3K pathway regulating cell proliferation, growth, and survival. Pseudogenes like ENSG00000233995 are non-functional genomic sequences that typically arise from duplication or retrotransposition events and do not encode functional proteins. The canonical drug target in oncology is the PIK3CA gene/protein, not its pseudogene.
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