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Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 2 (PAICSP2)

Target
PAICSP2
Molecular classification
Other
01

Overview

The sequence named "phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 2" (PAICSP2) designates a *pseudogene* related to enzymes involved in de novo purine biosynthesis (aminoimidazole carboxylase and succinocarboxamide synthetase, both sometimes found as a fused bifunctional enzyme in some species). Pseudogenes are DNA sequences similar to known genes but are typically *non-functional* due to mutations, truncations, or loss of regulatory elements. As such, PAICSP2 does **not** encode a functional protein, is **not a therapeutic target**, and currently has no established biological function, disease association, interacting drugs, or direct clinical relevance.\n\nThe enzymes this pseudogene is related to (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase) are genuine enzymes in purine metabolism, but PAICSP2 itself encodes no active enzyme. Pseudogenes can occasionally act in gene regulation or as genomic markers, but there is no evidence PAICSP2 has such a function.\n\nPAICSP2 is a *pseudogene* not representing a canonical drug target, lacks biological activity, and should generally not be used as a therapeutic target designation.

Other names
PAICSP2

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