phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 3 (PAICSP3)

PAICSP3 is formally described as a pseudogene derived from the fusion or colocation of two functional domains: phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase. These domains, when encoded in active genes, are essential enzymes in de novo purine biosynthesis, catalyzing sequential steps in the formation of inosine monophosphate (IMP). As a pseudogene, PAICSP3 does not produce functional protein and lacks enzymatic activity, thus it is not a valid therapeutic target, receptor, enzyme, or transporter. Its inclusion in target lists likely reflects a database artifact or misannotation, and the nomenclature combining two enzyme domains with "pseudogene" designator and a number suffix (3) is uncommon, making the entry potentially problematic for structured biochemical and pharmacological analysis. The underlying functional enzymes belong to the Enzyme class, particularly ligases/carboxylases, acting in purine biosynthesis. PAICSP3 itself is not implicated in biological function or disease, and does not interact with drugs. If structured information is required, this entry should be flagged as incorrect or non-target.

None applicable to the pseudogene.