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The plasma membrane is a dynamic, semi-permeable lipid bilayer that forms the outer boundary of cells, playing a critical role in maintaining cellular integrity, mediating communication with the environment, and regulating transport of substances into and out of the cell. Modulators targeting the plasma membrane do not act on a single protein or receptor but instead alter physical or organizational properties of the membrane itself—such as fluidity, lipid raft formation, curvature, and mechanical tension—to influence cellular function.
Alters physical state/fluidity/lipid organization/mechanical response of the plasma membrane, influencing protein activity and cellular signaling.
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