Plasma protein fraction (human)

Plasma protein replacement is a **therapeutic approach** rather than a single molecular target. It involves the transfusion or infusion of plasma-derived protein preparations—typically plasma protein fraction (human), which is a sterile mixture mainly composed of albumin and globulins derived from donated human plasma. These preparations are used to treat or mitigate **protein deficiencies** (such as losses from bleeding, burns, or liver failure), restore oncotic pressure, and act as adjuncts in procedures like **therapeutic plasma exchange** (plasmapheresis), where patient plasma is removed and replaced to treat autoimmune or hematological diseases. This approach is not "targeted" in the pharmacological sense but is essential in critical care and hematology for restoring key physiological functions of the plasma[4][3][5][1].

Other names

Human plasma proteinHuman plasma protein fractionPlasma protein fractionPlasma protein fraction humanPlasma protein fraction (human)

Restores plasma oncotic pressure and blood volume\nReplaces missing or deficient plasma proteins and coagulation factors[4]\nDilutes and removes pathogenic antibodies during plasma exchange procedures[3][1][5]