PMS1 homolog 2, mismatch repair system component pseudogene 11 (PMS2P11)

PMS1 homolog 2, mismatch repair system component pseudogene 11 (PMS2P11) is a **pseudogene**, located on chromosome 7q11.23, and is part of a locus that arises from readthrough transcription of multiple neighboring pseudogenes (DTX2P1, UPK3BP1, and PMS2P11)[1][3][5]. The transcripts from this locus are not believed to encode any functional protein[1][3][5]. PMS2P11 is distinct from the functional mismatch repair gene PMS2 and has no known role in mismatch repair, disease, or drug interactions[1][3][5]. The locus may also be referred to as DTX2P1-UPK3BP1-PMS2P11, representing a readthrough transcript that combines elements from several pseudogenes[1][3]. No evidence supports PMS2P11 as a therapeutic target, nor is it associated with known biological functions, disease relevance, or molecular activity[1][3][5]. This pseudogene must not be confused with the functional **PMS2** gene, which is crucial for DNA mismatch repair[2][4]. PMS2P11 is a pseudogene without protein-coding or therapeutic targeting potential[1][3][5].

Other names

PMS2P11PMS2L11PMS2-related protein 6PMSR6Putative postmeiotic segregation increased 2-like protein 11Putative postmeiotic segregation increased 2 pseudogene 11