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Poliovirus Type 1 Antigen (Inactivated)
- Molecular classification
- Vaccine Antigen
01
Overview
Poliovirus type 1 antigen (inactivated) is a purified, inactivated form of the poliovirus type 1, used as a component of inactivated polio vaccines (IPV). It stimulates the immune system to produce neutralizing antibodies, preventing viral spread and protecting against paralytic disease. The antigen is produced by propagating the virus in continuous lines of monkey kidney cells and then inactivating it with formaldehyde. It is administered via intramuscular or intradermal injection and has a highly favorable safety record.
02
Mechanism of action
Stimulates the immune system to produce neutralizing antibodies specific for poliovirus type 1, preventing viral spread to the central nervous system and protecting against paralytic disease.
03
Biological functions
Induction of neutralizing antibodiesActive Immunization
04
Disease associations
Infection
05
Safety considerations
Mild local reactions such as tenderness at injection site
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