Target intelligence / Profile preview

Poliovirus Type 1 Capsid Protein (Mahoney Strain)

Molecular classification: Structural Protein, Viral Capsid Protein

Overview

The poliovirus type 1 Mahoney strain’s capsid protein complex forms an essential protective shell around its RNA genome. Its major subunit—VP1—not only provides structural integrity but also enables specific interaction with human cellular receptors necessary for infection initiation. This makes it both a central player in pathogenesis and an ideal target for vaccine development efforts focused on safe yet highly immunogenic virus-like particles.

Other names: VP1VP2VP3VP4P1 polyprotein

Biological functions

Genome protectionHost cell attachmentHost cell entryImmunogenicity

Disease associations

PoliomyelitisInfection

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