Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Poly(ADP-ribose) Polymerase 7 (PARP7)
- Target
- PARP7
- Molecular classification
- Enzyme, Mono-ADP-ribosyltransferase, PARP Family
01
Overview
Poly(ADP-ribose) polymerase 7 (PARP7), also known as ARTD14 or TIPARP, is a member of the PARP family of enzymes and a mono-ADP-ribosyltransferase (MART). PARP7 plays roles in gene regulation, immune response modulation, and cancer biology. It catalyzes the transfer of single ADP-ribose units to target proteins and influences pathways like nuclear receptor signaling and interferon response.
- Other names
- ARTD14TIPARPTCDD-inducible poly(ADP-ribose) polymeraseTiPARP
02
Mechanism of action
Inhibition of mono-ADP-ribosyltransferase activity
03
Biological functions
Gene regulationImmune response modulationNuclear receptor signalingHistone modification
04
Disease associations
CancerInflammation
05
Safety considerations
Context-dependent effects in cancer (potential tumor promotion or suppression)Potential for off-target effects
06
Interacting drugs
RBN-2397
Beyond the preview
Go deeper on Poly(ADP-ribose) Polymerase 7 (PARP7).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Poly(ADP-ribose) Polymerase 7 (PARP7).