Target intelligence / Profile preview

POM121 transmembrane nucleoporin like 13, pseudogene (POM121L13P)

Target
POM121L13P
Molecular classification
Other (Pseudogene)
01

Overview

POM121 transmembrane nucleoporin like 13, pseudogene (POM121L13P) is a human gene annotated as a pseudogene, meaning it is a non-functional copy that resembles the POM121 gene but does not encode a functional protein due to disrupting mutations or loss of coding potential[1][4][6]. Like other pseudogenes, it may have regulatory functions at the transcriptional or epigenetic level, potentially impacting the expression of related genes, but it is not considered a druggable therapeutic target nor a classical receptor, enzyme, transporter, or other molecular target family member[2]. The only disease association currently listed is with gastric cardia adenocarcinoma, but this is likely based on the gene locus rather than direct functional involvement[4]. Key points: - POM121L13P is not a functional protein or receptor[1][6]. - It is classified as a pseudogene and is not a therapeutic target[1][2][4][6]. - It does not have known protein interactions, mechanisms of drug action, biomarker applications, or recognized safety concerns related to therapeutics.

Other names
POM121 membrane glycoprotein-like 13, pseudogenePOM121L13P
02

Biological functions

Other (No direct biological function as a protein due to loss of coding capability; general pseudogene regulatory roles possible)
03

Disease associations

Other (Associations reported with gastric cardia adenocarcinoma in some databases, but not a direct target)

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