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PPP2R2B intronic transcript 1 (non-protein coding) (PPP2R2B-IT1)
- Target
- PPP2R2B-IT1
- Molecular classification
- Long non-coding RNA (lncRNA), Other
01
Overview
PPP2R2B intronic transcript 1 (PPP2R2B-IT1) is a non-protein-coding long non-coding RNA transcribed from an intronic region of the PPP2R2B gene, which encodes a regulatory subunit of protein phosphatase 2A. As a lncRNA, PPP2R2B-IT1 does not act as a receptor, enzyme, or classical therapeutic target, but may participate in transcriptional regulation and potentially influence gene expression through chromatin modification or RNA-mediated regulatory mechanisms, as described for other intronic lncRNAs[3][4]. Its biological functions and therapeutic relevance are not well established, and there is no current evidence that PPP2R2B-IT1 serves as a direct drug target or biomarker.
- Other names
- PPP2R2B-IT1PPP2R2B intronic transcript 1 (non-protein coding)PPP2R2B intronic transcript 1
02
Biological functions
Transcriptional regulation (by lncRNA mechanisms), likely involved in modulating expression of PPP2R2B or neighboring genes[3][4]
03
Disease associations
Other (possible indirect involvement in neurodegenerative disease via PPP2R2B gene regulation)
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