PRAME family member 36, pseudogene (PRAMEF36P)

PRAME family member 36, pseudogene (PRAMEF36P) is a human pseudogene located at chromosomal position 1p36.21[1][2][3]. This locus is classified as a pseudogene, meaning it resembles a functional gene but has lost its ability to encode a protein due to accumulated mutations. As such, it does not encode a protein product and currently does not have any established biological function, known disease relevance, or role as a therapeutic target. This distinguishes it from protein-coding members of the PRAME gene family, which can have biological and pathological roles, including expression in cancer, but PRAMEF36P itself is not functionally annotated and has no aliases, functional classification, or clinical interest[1][2][3]. Key distinctions and notes: - PRAMEF36P should not be confused with other functional PRAME family genes (such as PRAME, PRAMEF1, PRAMEF2), which are protein-coding and studied for possible disease relevance[6][7][8]. - If used as a drug target or for study design, this entry is not appropriate since pseudogenes do not encode active druggable biomolecules. In summary, "PRAME family member 36, pseudogene" (PRAMEF36P) is a non-functional, non-protein-coding genomic locus, and is not a therapeutic target or functionally relevant molecule in human biology.

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