Target intelligence / Profile preview

Pregnancy specific beta-1-glycoprotein 10, pseudogene (PSG10P)

Target
PSG10P
Molecular classification
Other (pseudogene)
01

Overview

Pregnancy specific beta-1-glycoprotein 10, pseudogene (PSG10P) is a non-coding pseudogene member of the pregnancy-specific glycoprotein gene family within the carcinoembryonic antigen (CEA) superfamily, located on human chromosome 19. Several PSG family members, including PSG10P, have arisen via gene duplication events, with many becoming functionally inactive pseudogenes containing premature stop codons or frame shifts[1][2]. The functional PSGs (like PSG1, PSG9, PSG12) are secreted glycoproteins produced by placental syncytiotrophoblasts, functioning mainly in immunomodulation during pregnancy[3][4]. However, PSG10P itself does not encode a protein and is not known to have biological or disease-related functions. Key clarification: - The term “pregnancy specific beta-1-glycoprotein 10, pseudogene” is valid as a gene symbol/entity, but *not* as a valid therapeutic target. - If your use case requires protein-coding/therapeutically actionable targets, **PSG10P is not suitable, and this entry should be flagged as incorrect for that application**. Note: This entry should be clearly differentiated from protein-coding PSG family members (such as pregnancy specific beta-1-glycoprotein 1 or PSG1) which have well-established biological and clinical roles[3][4].

Other names
Pregnancy specific beta-1-glycoprotein 12Pregnancy specific beta-1-glycoprotein 120PSG12 psiPSG10 pseudogene
02

Mechanism of action

None (pseudogenes do not have mechanisms of action as drug targets)

03

Biological functions

None (as a pseudogene, PSG10P does not produce a functional protein and has no established physiological or biochemical functions)
04

Disease associations

None (there is no evidence indicating involvement in disease; in contrast, functional PSGs may serve as biomarkers or have immunomodulatory roles[1][3][4])
05

Safety considerations

None (no therapeutic targeting, no drug interaction or safety profile)
06

Interacting drugs

None (no drugs are known to interact with this pseudogene)
07

Biomarkers

None (in contrast, some circulating PSGs, such as PSG1, can serve as biomarkers in pregnancy or cancer, but this does not apply to PSG10P[3][4])

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